derail

1. V-T To derail something such as a plan or a series of negotiations means to prevent it from continuing as planned. 打乱 (原定计划)[journalism]

The present wave of political killings is the work of people trying to derail peace talks. 现在的政治谋杀浪潮是那些试图破坏和平谈判进程的人所为。

2. V-T/V-I If a train is derailed or if it derails, it comes off the track on which it is running. 脱轨

At least six people were killed and about twenty injured when a train was derailed in an isolated mountain region. 火车在一片偏僻的山区脱轨，导致至少六人死亡，约二十人受伤。