Aceclofenac

常见例句

• Objective To prepare aceclofenac pellet(AFP).
  目的 制备醋氯芬酸微丸。
• Aceclofenac was synthesized in 82% overall yield from sodium diclofenac and t-butyl chloroacetate viaesterification and hydrolysis.
  双氯芬酸钠与氯乙酸叔丁酯经酯化、水解反应制得非甾体抗炎药醋氯芬酸,收率82%25。
• OBJECTIVE：To study the therapeutic effect on adjuvant-induced arthritis and inhibitory effect on delayed type hypersensitivity(DTH) of aceclofenac.
  目的：研究醋氯芬酸对佐剂关节炎大鼠的治疗作用及对迟发型超敏反应的抑制作用。
• Aceclofenac also suppressed DTH with SRBC or PC in mice when it was administered after antigen challenge,but it had no marked effect when administered before antigon challege.
  醋氯芬酸于抗原攻击后给药，显著抑制SRBC或PC所致小鼠迟发型超敏反应，而抗原攻击前给药则无明显作用。
• Method:Aceclofenac was synthesized from chloroacetic acid and benzyl alcohol by esterification to give benzyl chloroacetate,which subjected to condensation and hydrogenolysis.
  方法:以氯乙酸为原料,和苯甲醇进行酯化反应合成氯代乙酸苄基酯,再经缩合、氢解反应制得目标化合物。
• CONCLUSION:Aceclofenac exerted marked therapeutic activity against adjuvant-induced arthritis,associated with its inhibiton to inflammatory response and DTH.
  结论：醋氯芬酸对大鼠佐剂关节炎具有治疗作用，其作用机制可能与其抗炎作用及对迟发型超敏反应的抑制作用有关。
返回 Aceclofenac